The role of T cell receptor signal intensity in T helper 17 cell development

T-helper (Th) 17 cells are a subset of CD4+ T cells defined through the release of the cytokine interleukin-17a (IL-17a). Activation of these cells is critical for protection against some extracellular bacterial and fungal pathogens. However, a dysregulated Th17 response targeted against self is tho...

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Bibliographic Details
Main Author: Tibbitt, Christopher Andrew
Published: University of Newcastle upon Tyne 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.682582