Manipulation of VEGF-A mRNA splicing repertoire as a potential therapeutic strategy in glomerular disease

Aims: Vascular endothelial growth factor (VEGF-A) is differentially spliced to give two functionally different isoform families, the pro-angiogenic, pro-permeability VEGFxxx and the anti-angiogenic, anti-permeability VEGFxxxb families. Evidence suggests that the balance of pro- and anti-angiogenic i...

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Bibliographic Details
Main Author: Stevens, Megan
Published: University of Bristol 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.682341