Molecular mechanisms and outcomes of arsenic-induced histone acetylation and microRNA regulation in cellular transformation
Chronic exposure to arsenic causes negative health outcomes, particularly malignant neoplasms of the skin, lung and bladder. Although epidemiological data has associated arsenic exposure to cancer, a clear molecular mechanism has remained elusive. This thesis studied the impact of arsenic trioxide (...
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Imperial College London
2015
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.682079 |