Molecular mechanisms and outcomes of arsenic-induced histone acetylation and microRNA regulation in cellular transformation

Chronic exposure to arsenic causes negative health outcomes, particularly malignant neoplasms of the skin, lung and bladder. Although epidemiological data has associated arsenic exposure to cancer, a clear molecular mechanism has remained elusive. This thesis studied the impact of arsenic trioxide (...

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Bibliographic Details
Main Author: Rahman, Sunniyat
Other Authors: Hajji, Nabil
Published: Imperial College London 2015
Subjects:
610
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.682079