Integrating immune cell functions and apoptosis-based therapies for the treatment of ovarian cancer

High levels of regulatory T cells (Treg cells) restrict immune responses against cancer cells and are associated with adverse outcomes in patients with ovarian cancer. Treg cell development and function is regulated by the transcription factor Foxp3. Studies into the regulation of Foxp3 may identify...

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Bibliographic Details
Main Author: Tuthill, Mark
Other Authors: Walczak, Henning ; Merkenschlager, Matthias
Published: Imperial College London 2013
Subjects:
610
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.682035