Investigation of how endoplasmic reticulum stress causes insulin resistance and neuroinflammation

Endoplasmic reticulum (ER) stress is caused by the accumulation of mis/unfolded proteins in the ER. ER stress signalling pathways termed the unfolded protein response are employed to alleviate ER stress through increasing the folding capacity and decreasing the folding demand of the ER as well as re...

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Bibliographic Details
Main Author: Brown, Max Adam
Published: Durham University 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.681758