Functional implications of tau-fyn interactions in Alzheimer's disease
Alzheimer’s disease (AD) is characterised by neuropathological deposits of amyloid plaques and neurofibrillary tangles. In AD, tau is abnormally phosphorylated and forms aggregates which spread trans-synaptically throughout the brain. The non-receptor-associated tyrosine kinase fyn is up-regulated i...
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King's College London (University of London)
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.677193 |