Mechanism of DC-SIGN mediated enhancement of HIV-1 infection

This thesis describes an investigation of the mechanisms by which DC-SIGN mediates enhancement of HIV-1 infection. Mannose-binding C-type lectin receptors, expressed on Langerhans cells and subepithelial dendritic cells (DCs), play an important role in HIV-1capture and subsequent dissemination to ly...

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Bibliographic Details
Main Author: Scala, Carlo
Other Authors: Kelly, Charles George ; Naglik, Julian Richard
Published: King's College London (University of London) 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.677098