An investigation into the role of microvesicles in mutant p53 invasive gain-of-function

p53 is a transcription factor with tumour suppressive attributes which is known to be mutated in over half of human cancers. As well as compromising the ability of p53 to function as a transcription factor, mutations in p53 often result in a gain-of-function phenotype which is characterised by incre...

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Bibliographic Details
Main Author: Heath, Nikki
Published: University of Glasgow 2015
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.676563