Analysis of a viral protease to study cellular pathways
The ovarian tumour (OTU) domain present at the N-terminus of the nairoviral L protein has been shown to deconjugate ubiquitin and interferon-stimulated gene 15 protein (ISG 15) from cellular proteins, thereby interfering with innate immune cell signalling pathways. I have confirmed and extended thes...
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Ulster University
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.674918 |