Development of selective inhibitors of dihydrofolate reductase (DHFR) of Mycobacterium tuberculosis

Mycobacterium tuberculosis is the causative organism for one of the pandemic diseases in the world, tuberculosis (TB). The length of treatment often results in multi-drug resistance (MDR) and patient non-compliance. One of the most important enzymes as a drug target for tuberculosis is dihydrofolate...

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Bibliographic Details
Main Author: Alfaraj, Rihaf
Other Authors: Threadgill, Michael ; Lloyd, Matthew ; Thompson, Andrew
Published: University of Bath 2013
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.669020