Design and synthesis of human dimethylarginine dimethylaminohydrolase (DDAH) inhibitors and development of a novel DDAH activity assay
Nitric oxide (NO) is a key physiological messenger, but an excessive production of this molecule can be detrimental, leading to the onset or worsening of many pathological conditions. Dimethylarginine dimethylaminohydrolase (DDAH) is a key enzyme in the NO pathway, involved in the metabolism of asym...
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University of Aberdeen
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.668984 |