Regulation of L-type Ca2+ channels by nitric oxide signalling in guinea pig ventricular myocytes

Nitric oxide (NO) is constitutively generated by cardiac myocytes and has important roles in cardiac function, including modifying L-type Ca2+ currents (ICa,L). The precise nature of this modification remains elusive with NO reported to increase, reduce or have biphasic effects on ICa,L. Here I expl...

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Bibliographic Details
Main Author: Weli, Sardar Mohammed
Other Authors: Davies, Noel; Mitcheson, John
Published: University of Leicester 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.666670