An investigation of the role of the MDM2-NME interaction in cancer cells
MDM2 is a proto-oncogene well known for its role as a negative regulator of the p53 tumour suppressor. It has also been demonstrated that co-upregulation of MDM2 and wild-type p53 is linked with reduced disease specific survival in renal cell carcinoma (RCC). Moreover, MDM2 expression has been shown...
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University of Liverpool
2014
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.664334 |