CAG.CTG trinucleotide repeat instability in the E.coli chromosome
In order to identify the molecular basis of genetic instability, a polymerization-independent strategy is developed to generate expanded repeat arrays. The repeat tracts are integrated in the 5’end of <i>lacZ</i> gene in the <i>Escherichia coli</i> chromosome. Using this mode...
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University of Edinburgh
2006
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.664197 |