Studying and manipulating chromatin motion in mammalian cells

I have investigated the range of chromatin motion in living human cells. I have shown that Lac Operator arrays tagged with GFP-LacI are able to move up to 2-3 µm over the period of two hours and on average, 0.2µm per second. These distances are greater than previously reported and similar to motion...

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Bibliographic Details
Main Author: Thomson, Inga
Published: University of Edinburgh 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.662904