Gene targeting and insertional mutagenesis in embryonic stem cells

Mutations are important in the study of gene function. Until recently mouse mutants available for study were spontaneous mutations and those derived from chemical or X-ray mutagenesis. Transgenic technology brought about the creation of more mouse mutants through insertional mutagenesis by retrovira...

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Bibliographic Details
Main Author: Sutherland, Helen F.
Published: University of Edinburgh 1992
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.662624