Gene targeting in mouse embryonal stem cells
This thesis is concerned with 'Hit and Run' gene targeting in ES cells, a method designed with the objective of introducing small mutations into the genome. The procedure relies on the integration of a vector carrying the desired mutation, and positive and negative selectable markers. Afte...
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University of Edinburgh
1995
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.660507 |