Investigation of contaminants with immunomodulatory activity in coagulation factor concentrates

The results demonstrate that all conventional and ion-exchange chromatographically purified coagulation factor concentrates inhibit lymphocyte proliferation <I>in vitro. </I>These concentrates also contain measurable amounts of active TGF-β. In contrast, immunoaffinity purified and recom...

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Bibliographic Details
Main Author: Pearson, Helen
Published: University of Edinburgh 1997
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.660489