The role of surface amino acid residues in protein folding and stability

Colicin A is a plasmid encoded bacteriocin produced by Escherichia coli (E. coli) regarded as a potential antibiotic. Colicin A is unusual in that it requires acidic lipids for its activity and its pore-forming domain (ColA-P) forms an acidic molten globule state. Previously it was shown that surfac...

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Bibliographic Details
Main Author: Huang, Yan
Published: University of Newcastle upon Tyne 2014
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.658353