Identification and functional analysis of the spindle checkpoint component mad³⁺ in Schizosaccharomyces pombe

The spindle checkpoint delays the metaphase to anaphase transition in response to spindle and kinetochore defects. Genetic screens in budding yeast originally identified the Mad and Bub proteins (and later the Mps1 kinase) as being core components of this conserved regulatory pathway. This work desc...

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Bibliographic Details
Main Author: Millband, David Nicholas
Published: University of Edinburgh 2001
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.657776