Functional analysis of the methyl-CpG-binding DNA glycosylase MBD4

The methyl-CpG-binding domain protein MBD4 can bind to methylated DNA and has glycosylase activity against thymine or uracil mismatched with guanine, preferentially within a CpG site (Hendrich <i>et al.,</i> 1999). This particular combination of activities indicates that MBD4 may be invo...

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Bibliographic Details
Main Author: Millar, Catherine Bridget
Published: University of Edinburgh 2002
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.657768