Class-specific monoclonal antibodies for the detection of O⁶-alkyl-2'-deoxyguanosines

The reaction of alkylating reagents with DNA yields a variety of potential mutagenic and carcinogenic lesions. One such group, the O<SUP>6</SUP>alkyl-2'-deoxyguanosines (O<SUP>6</SUP>alkyl dGs) are known to induce guanine to adenine transitions, which may lead to the act...

Full description

Bibliographic Details
Main Author: McPhillips, Fiona
Published: University of Edinburgh 1994
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.657131