Differential tumour necrosis factor signalling in human models of acute lung injury
Numerous clinical and experimental studies have implicated tumour necrosis factor (TNF) as a central mediator of acute lung injury (ALI). TNF signals through two cell surface receptors, TNFR1 and TNFR2, which initiate distinct signalling pathways and cellular responses. Using a novel, highly selecti...
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Imperial College London
2014
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.656757 |