Plasmacytoid dendritic cell activation and differentiation by the Human Immunodeficiency Virus type 1 and 2 : implications for HIV immunopathogenesis

Infection with HIV-1 results in the progressive dysfunction of the immune system eventually leading to AIDS, characterised by low CD4+ T lymphocyte counts and increased susceptibility to opportunistic infections. In contrast to HIV-1, individuals infected with HIV-2 often remain asymptomatic, with l...

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Bibliographic Details
Main Author: Royle, Caroline
Other Authors: Boasso, Adriano; Bangham, Charles
Published: Imperial College London 2014
Subjects:
610
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.656619