Shear stress and interferon regulatory factor 5 modulate myeloid cell behaviour in atherosclerosis

Rupture of 'vulnerable' atherosclerotic plaques and subsequent thrombosis cause acute cardiovascular events, and can develop upon exposure of the arterial wall to low shear stress. Myeloid cells - the main inflammatory cells within atherosclerotic plaques - are heterogeneous; ranging from...

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Bibliographic Details
Main Author: Seneviratne, Anusha
Other Authors: Monaco, Claudia; Krams, Rob
Published: Imperial College London 2014
Subjects:
610
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.656556