Single molecule studies on actin folding by the eukaryotic chaperonin CCT
The eukaryotic, cytosolic chaperonin containing TCP-1 (CCT) is a protein folding nanomachine. CCT is a 1 MDa double-ring-structured ATPase which assists nascent polypeptides to reach their native conformational state. Obligate substrates include the cytoskeletal components actin and tubulin. Whilst...
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Imperial College London
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.656528 |