Chemical and biological investigation of iterative PKS-NRPS programming during aspyridone and tenellin biosynthesis

Hybrid polyketide-nonribosomal peptides are one of the important classes of fungal natural products. The aim of this work was to investigate the programming behaviour of the iterative enzymes of PKS-NRPS and delineate biosynthetic steps of PKS-NRPS compounds. This work involves isolation and structu...

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Bibliographic Details
Main Author: Wasil, Zahida
Published: University of Bristol 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.654536