Integrin affinity modulation by Ras signalling molecules

In this thesis I have sought to understand the mechanism by which H-Ras and its effectors modulate integrin affinity. H-Ras is a member of the Ras superfamily of small GTP binding proteins. Expression of the constitutively active variant of H-Ras (Ras G12V) within an integrin affinity reporter syste...

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Bibliographic Details
Main Author: Lad, Yatishkumar
Published: University of Edinburgh 2002
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.653604