The role of DNA repair gene Ercc1 in the liver

AdenoCre infection of hepatocyte cultures led to high levels of recombination with no ERCC1 protein remaining at 48 hours after infection. Flow cytometry failed to show high levels of polyploidy in knockout hepatocytes 1 week after infection. This differed from the premature polyploidy seen in this...

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Bibliographic Details
Main Author: Kirschner, Kristina
Published: University of Edinburgh 2007
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.653474