Design and synthesis of novel protecting groups for the solid phase synthesis of oligonucleotides

Four different compounds have been investigated for their usefulness as protecting groups for the solid phase synthesis of RNA and DNA, covering both 5' and 2' protection. First is a 5' hydroxyl protecting group containing the highly hydrophobic Tbf (Tetrabenzo[a,c,g,i]fluorene) moiet...

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Bibliographic Details
Main Author: Kerr, Ruairidh Duncan
Published: University of Edinburgh 2000
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.653316