Adoptive immunotherapy for Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease

The aim of this study was to establish a pre-clinical SCID mouse model of PTLD in which to test CTL immunotherapy. EBV <i>in vitro</i> infected B lymphoblastoid cell lines (BLCLs) were used to give rise to PTLD-like lesions in SCID mice. A minimum dose of 2x10<sup>6</sup> BLC...

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Bibliographic Details
Main Author: Johannessen, Ingólfur
Published: University of Edinburgh 2007
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.653019