The application of lipase mediated resolutions to the synthesis of the optical isomers of bufuralol and methadone
This thesis describes the application of lipase mediated kinetic resolutions in the synthesis of two biologically active and pharmaceutically important compounds :- Bufuralol has activity as a beta-blocker and recently it has become useful in metabolism studies as a substrate for a specific cytochro...
Main Author: | Hull, Jonathan David |
---|---|
Published: |
University of Edinburgh
2000
|
Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.652705 |
Similar Items
-
The metabolism and kinetics of fenfluramine, its optical isomers and a structural analogue, benfluorex
by: Richards, R.
Published: (1985) -
Evaluating the potential neurotoxicity of hexanedione isomers: An in vitro approach
by: Zilz, Thomas R.
Published: (2008) -
Implications of trans isomers of arachidonic and eicosapentaenoic acids on immune / inflammatory cell activity
by: Higgs, Warren
Published: (2002) -
Applications of lipase-catalyzed kinetic resolution of trans- and cis-2-phenyl-cycloproane-1-carboxylic azolides to prepare optically pure isomer
by: Yan Ru Ye, et al.
Published: (2017) -
The binding ability of alpha-1-acid glycoprotein as a mechanism of resistance to methadone
by: Behan, Jennifer L.
Published: (2010)