The application of lipase mediated resolutions to the synthesis of the optical isomers of bufuralol and methadone
This thesis describes the application of lipase mediated kinetic resolutions in the synthesis of two biologically active and pharmaceutically important compounds :- Bufuralol has activity as a beta-blocker and recently it has become useful in metabolism studies as a substrate for a specific cytochro...
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University of Edinburgh
2000
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.652705 |