The application of lipase mediated resolutions to the synthesis of the optical isomers of bufuralol and methadone

This thesis describes the application of lipase mediated kinetic resolutions in the synthesis of two biologically active and pharmaceutically important compounds :- Bufuralol has activity as a beta-blocker and recently it has become useful in metabolism studies as a substrate for a specific cytochro...

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Bibliographic Details
Main Author: Hull, Jonathan David
Published: University of Edinburgh 2000
Subjects:
615
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.652705