Molecular and cell genetic analysis of chromosome 11 in sporadic epithelial ovarian cancer

I used PCR based polymorphic microsatellites to define frequent loss of heterozygosity (LOH) at 11p15.5-15.1 and 11q23-qter in DNA blood/tumour pairs from 60 patients with ovarian neoplasms. LOH at 11q23-qter was significantly associated with advantaged stage and adverse actuarial survival. Integrat...

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Bibliographic Details
Main Author: Gabra, Hani
Published: University of Edinburgh 1997
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.651174