The effect of social isolation and leptin on the hypothalamo-pituitary-adrenocortical (HPA) response to acute stress in rats
The hypothalamo-pituitary-adrenal (HPA) axis is the main regulator of stress in mammals, and prolongation of the stress response can lead to manifestation of metabolic and psychiatric disorders. Leptin is an adipokine known to act at the hypothalamus to regulate body fat stores, appetite and energy...
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Imperial College London
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.650641 |