Synthesis and biological evaluation of histone lysine methyltransferase inhibitors
The epigenetic component of cancer is now well-established and epigenetic therapeutics targeting histone deacetylase and DNA methyltransferase enzymes have received FDA approval. Histone lysine methyltransferases (HKMTs) are a new and promising epigenetic target class for cancer treatment, but the s...
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Imperial College London
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.650593 |