Protein-protein interactions in GnRH receptor signalling

Human embryonic kidney (HEK) 293 cells, stably expressing the rat GnRH receptor were used to investigate the mechanism of ERK activation by GnRH.  ERK activation was found to be dependent on cell adhesion to the extracellular matrix, and required an intact actin cytoskeleton. Through the use of spec...

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Bibliographic Details
Main Author: Davidson, L.
Published: University of Edinburgh 2005
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.649167