The structure and interactions of pneumolysin

Pneumolysin is a major virulence factor of Streptococcus pneumoniae. It is a 53-kDa protein with four domains which form pores in host cells and depletes serum-complement resulting in a diminished host immune response. Despite its importance, the high-resolution structure of pneumolysin is yet to be...

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Bibliographic Details
Main Author: Marshall, Jamie Elton
Other Authors: Wallis, Russell; Andrew, Peter
Published: University of Leicester 2015
Subjects:
579
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.647123