Relationships between nuclear lamins and telomere biology in progeroid laminopathies and cancer
Telomeres are essential for maintaining the integrity of the genome. Shortening and dysfunction of telomeres initiates cellular senescence, halting further cell division, and instigating alterations in biological processes which contribute to ageing. Progeroid syndromes are disorders of ageing. Pati...
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University of Leicester
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.647119 |