The functional assembly of the mammalian minichromosome maintenance complex
The minichromosome maintenance complex (MCM2-7) is the putative DNA helicase in eukaryotes, and is essential for DNA replication. Mis-regulation of its assembly and function can lead to genomic instability, replication stress and genome re-replication, which are powerful drivers toward the acquisiti...
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University of York
2014
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.647070 |