Role of fascin in regulating microtubule and focal adhesion dynamics in carcinoma cells

Fascin is an actin-bundling protein whose upregulation is correlated with poor prognosis in cancer. Previous studies have shown a role for fascin in regulating assembly of actin bundles and stability of adhesion structures. Fascin has not previously been localised at focal adhesions and the mechanis...

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Bibliographic Details
Main Author: Villari, Giulia
Other Authors: Parsons, Madeline ; Jones, Gareth E.
Published: King's College London (University of London) 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.646969