Csk is an important negative regulator of phagocyte responsiveness in vivo : characterisation of myeloid cell-specific Csk deficiency in mice by conditional mutagenesis (Cre/loxP)
Whilst the recruitment of phagocytic leukocytes is fundamental to the innate response against pathogenic infection, the inappropriate mobilisation of their cytotoxic potential can also lead to fatal tissue injury. To determine the contribution of Csk, a negative regulator of Src family kinases, to t...
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University College London (University of London)
2007
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.644405 |