Loss of heterozygosity on chromosome 17 and p53 mutation in primary human breast cancer

A high frequency of LOH (61%) has been detected in a series of breast tumours at a site at a 17p13.3 suggesting the presence of a tumour suppressor gene involved in breast cancer on chromosome 17p (Mackay <I>et al., </I>1988a). Following on from this work the incidence of LOH in primary...

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Bibliographic Details
Main Author: Coles, Christopher
Published: University of Edinburgh 1994
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.643329