Structural study of the adenylation domain by molecular dynamics simulation

As antibiotic resistance is increasing more rapidly than new antibiotics are produced and/or discovered, there is an increasing need to identify new ways to design novel antibiotics. A potential avenue for this, is the exploitation of Nonribosomal Peptide Synthetases (NRPSs) from bacteria and fungi...

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Bibliographic Details
Main Author: Thalassinou, Joanne Frances
Published: University of Warwick 2012
Subjects:
540
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.640930