Design and synthesis of IKK1 inhibitors for the treatment of hormone refractory prostate cancer
The transcription factor NF-κB (Nuclear Factor kappa B) mediates the expression of a number of pro-inflammatory cytokines, adhesion molecules, growth factors, and anti-apoptosis survival proteins. NF-κB transcriptional activity is normally suppressed in the cytosol via complexation with its natural...
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University of Strathclyde
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.640862 |