Towards the total synthesis of vibralactone and the miuraenamides

This thesis describes the efforts made towards the total synthesis of vibralactone and the miuraenamides. Initially, the attempted synthesis and derivatisation of vibralactone, a pancreatic lipase inhibiting fused bicyclic β-lactone, will be discussed. Vibralactone provides an interesting synthetic...

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Bibliographic Details
Main Author: Heap, Robert
Other Authors: Brown, Richard
Published: University of Southampton 2014
Subjects:
540
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.640732