The role of the autoimmune regulator gene (AIRE) in peripheral T cells
Mutations of the autoimmune regulator gene (AIRE) lead to the development of the multiple organ specific autoimmune disease, autoimmune polyendocrine syndrome type 1 (APS1). Aire is known to have a role in central tolerance through regulating the expression of self-antigens in the thymus. Prevention...
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University of Edinburgh
2004
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.640204 |