Synthesis, DNA interactions and cytotoxicity of novel chloroethylaminoanthraquinones

The design of DNA directed nitrogen mustards has led to the development of compounds with increased specificity for DNA and enhanced cytotoxicity compared to similar untargeted mustards. By linking an intercalating anthraquinone chromophore to a nitrogen mustard function it was anticipated that such...

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Bibliographic Details
Main Author: Paniwnyk, Zennia
Published: De Montfort University 2000
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.640164