Synthesis, DNA interactions and cytotoxicity of novel chloroethylaminoanthraquinones
The design of DNA directed nitrogen mustards has led to the development of compounds with increased specificity for DNA and enhanced cytotoxicity compared to similar untargeted mustards. By linking an intercalating anthraquinone chromophore to a nitrogen mustard function it was anticipated that such...
Main Author: | |
---|---|
Published: |
De Montfort University
2000
|
Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.640164 |