Identification of cancer genes using Sleeping Beauty mutagenesis of the Ptch1 murine tumour model

Medulloblastoma (MB) is a paediatric tumour of the cerebellum which is responsible for 15-20% of all childhood brain tumours. Mortality due to this disease is high (~40%) and successful treatment is associated with significant neurological and cognitive consequences, making new therapies desirable....

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Bibliographic Details
Main Author: Al-Afghani, Hani Mohammad A.
Published: University of Newcastle upon Tyne 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.639813