Role of proteinase-activated receptor-1-dependent secondary mediators in lung fibrosis
Persistent local activation of the coagulation cascade typifies tibroproliferative lung disorders such as idiopathic pulmonary fibrosis and the acute respiratory distress syndrome. In addition to its role in coagulation, thrombin exerts potent pro inflammatory and pro-flbrotic effects via activation...
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University College London (University of London)
2007
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.639534 |